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Ana Lúcia Fachin Selected Research

Chalcones

10/2021Trans-chalcone suppresses tumor growth mediated at least in part by the induction of heme oxygenase-1 in breast cancer.
8/2021Development, Characterization and Cell Viability Inhibition of PVA Spheres Loaded with Doxorubicin and 4'-Amino-1-Naphthyl-Chalcone (D14) for Osteosarcoma.
8/2018Chalcones Repressed the AURKA and MDR Proteins Involved in Metastasis and Multiple Drug Resistance in Breast Cancer Cell Lines.
1/2018Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition.
10/2016Anti-cancer activity of trans-chalcone in osteosarcoma: Involvement of Sp1 and p53.

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Ana Lúcia Fachin Research Topics

Disease

9Neoplasms (Cancer)
10/2021 - 03/2013
5Infections
06/2020 - 02/2009
4Osteosarcoma (Osteogenic Sarcoma)
08/2021 - 10/2016
3Breast Neoplasms (Breast Cancer)
10/2021 - 01/2017
3Neoplasm Metastasis (Metastasis)
09/2018 - 10/2016
2Fibromyalgia (Fibrositis)
02/2012 - 03/2010
1Seizures (Absence Seizure)
03/2021
1Mycoses (Diseases, Fungus)
12/2020
1Tinea (Ringworm)
06/2020
1Colorectal Neoplasms (Colorectal Cancer)
06/2018
1Stomach Neoplasms (Stomach Cancer)
01/2018
1Trichophyton infection
03/2016
1Anxiety Disorders (Anxiety Disorder)
02/2014
1Carcinoma (Carcinomatosis)
03/2013
1Pain (Aches)
02/2012
1Tuberculosis (Tuberculoses)
01/2009
1Inflammation (Inflammations)
01/2009
1Necrosis
01/2009

Drug/Important Bio-Agent (IBA)

7Chalcone (Benzalacetophenone)IBA
10/2021 - 10/2016
5ChalconesIBA
10/2021 - 10/2016
3Keratins (Keratin)IBA
06/2020 - 03/2016
3Proteins (Proteins, Gene)FDA Link
05/2019 - 02/2009
2AntioxidantsIBA
10/2021 - 12/2013
2BromidesIBA
08/2021 - 03/2013
2Anti-Anxiety Agents (Anxiolytics)IBA
03/2021 - 02/2014
2ElastinIBA
05/2019 - 03/2016
2licochalcone AIBA
08/2018 - 01/2017
2CurcuminIBA
06/2018 - 01/2018
2Catechol O-Methyltransferase (Methyltransferase, Catechol)IBA
02/2012 - 03/2010
1Small Interfering RNA (siRNA)IBA
10/2021
1Heme Oxygenase-1IBA
10/2021
1Biological ProductsIBA
10/2021
1PhytochemicalsIBA
10/2021
1Therapeutic UsesIBA
10/2021
1Doxorubicin (Adriamycin)FDA LinkGeneric
08/2021
1NitrogenIBA
08/2021
1PolyphenolsIBA
08/2021
1Pentylenetetrazole (Metrazol)IBA
03/2021
1Hypnotics and Sedatives (Sedatives)IBA
03/2021
1Kainic Acid (Kainate)IBA
03/2021
1Pilocarpine (Ocusert)FDA LinkGeneric
03/2021
1PicrotoxinIBA
03/2021
1MicroRNAs (MicroRNA)IBA
12/2020
1Histone Deacetylase InhibitorsIBA
06/2020
1Amphotericin B (Amphotericin)FDA LinkGeneric
06/2020
1Antifungal AgentsIBA
06/2020
1Fluconazole (Zonal)FDA LinkGeneric
06/2020
1Ergosterol (Lumisterol)IBA
06/2020
1Terbinafine (Lamisil)FDA LinkGeneric
11/2019
1Aurora Kinase AIBA
08/2018
1Messenger RNA (mRNA)IBA
06/2018
1Cytotoxins (Cytolysins)IBA
06/2018
1Transcription Factors (Transcription Factor)IBA
06/2018
1AnthelminticsIBA
01/2018
1Pharmaceutical PreparationsIBA
01/2018
1Tumor Suppressor Protein p53IBA
01/2018
1FlavonoidsIBA
12/2013
1voacangineIBA
03/2013
1Indole AlkaloidsIBA
03/2013
1AlkaloidsIBA
03/2013
1coronardineIBA
03/2013
1DNA (Deoxyribonucleic Acid)IBA
02/2012
1Serotonin ReceptorsIBA
03/2010
1Interleukin-17 (Interleukin 17)IBA
01/2009
1Transforming Growth Factor beta (TGF-beta)IBA
01/2009
1CytokinesIBA
01/2009
1Interleukin-6 (Interleukin 6)IBA
01/2009
1Heat-Shock Proteins (Heat-Shock Protein)IBA
01/2009
1VaccinesIBA
01/2009
1Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA
01/2009
1Lymphotoxin-alpha (Lymphotoxin)IBA
01/2009

Therapy/Procedure

7Therapeutics
06/2020 - 01/2009
1Drug Therapy (Chemotherapy)
01/2019